Risk assessing human infection of avian influenza A H5N6 through influenza risk assessment tool (IRAT)
Risk assessing human infection of avian influenza A/H5N6 through influenza risk assessment tool (IRAT)
Division of Influenza Virus, Center for Infectious Disease, NIH, CDC
Kim Heui Man, Kim Chi-Kyeong, Lee Joo-Yeon, Kim Kisoon
The IRAT was designed to obtain information about two questions. One is, ‘‘What is the risk that a virus not currently circulating in the human population has the potential for sustained human-to-human transmission?’’ The second question is, ‘‘If the virus were to achieve sustained human-to-human transmission, what is the risk that a virus not currently circulating in the human population has the potential to significantly impact public health?’’ The IRAT consists of 10 evaluation criteria grouped within three overarching categories which are: properties of the virus; attributes of the population; and ecology and epidemiology. In this paper, 10 criteria were introduced and some experimental elements were applied to recently isolated H5N6 avian influenza in Korea.