Antimicrobial Stewardship Program (ASP*)
* Antimicrobial Stewardship Program
Meaning
- A management system aimed at reducing inappropriate antibiotic use and promoting appropriate use by deploying a specialized management team to intervene and manage the antimicrobial prescribing process within healthcare institutions
Necessity
- Antimicrobial overuse and misuse are major causes of antimicrobial resistance.
- There is a need for strategies to strengthen appropriate antimicrobial prescribing in healthcare institutions, considering the current state of antimicrobial use in the country.
Key elements for implementing ASP (Antimicrobial Stewardship Program) in healthcare institutions in South Korea
- Interest and resource support from hospital management
- Formation and operation of a multidisciplinary ASP dedicated team, including responsible physicians and dedicated pharmacists
- Implementation of antimicrobial prescribing interventions
- Tracking studies to evaluate the effectiveness of antimicrobial prescribing interventions
- Sharing the results of tracking studies with medical staff and management
- Conducting education to improve antimicrobial use
Antimicrobial prescribing intervention activities
Key strategies
| Category | Content |
|---|---|
| Antimicrobial use Audit and feedback |
A strategy in which the manager evaluates the appropriateness of antimicrobial selection, duration of prescription, and dosage after antimicrobials are prescribed |
| Antimicrobial prescription restrictions and pre-approval programs |
A strategy in which medical staff obtain approval from management before prescribing specific antimicrobials to patients |
Additional strategies
- Utilizing “antimicrobial prescribing forms” or “computerized systems” to support antimicrobial prescribing
- Recommendations for antimicrobial de-escalation or step-down therapy, and optimal duration of antimicrobial therapy
- Switching from intravenous antimicrobials to oral administration, and utilizing therapeutic drug monitoring for specific antimicrobials
- Rapid reporting of microbial test results

ASP Integrated Operation Guidelines (2023)
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